Can pregnant women use valerian root safely?

Published: October 16, 2025
Updated: October 16, 2025

Pregnant women should avoid valerian root completely because of significant safety concerns. It is contraindicated universally by reputable health organizations on the basis that substances in it, like the valepotriates, might stimulate the uterus into contractions and could traverse the placental barrier. There have been no studies involving the human species to confirm its safety during pregnancy. Avoidance is therefore the only prudent course to pursue.

Pregnancy Safety Comparison: Herbal Remedies
HerbValerian RootPregnancy SafetyContraindicatedKey Concerns
Uterine stimulation, fetal development risks
HerbChamomilePregnancy SafetyLimited use after 1st trimesterKey Concerns
Possible allergen, avoid large amounts
HerbGingerPregnancy SafetyGenerally safeKey Concerns
Avoid high doses near delivery
HerbPeppermintPregnancy SafetyGenerally safeKey Concerns
Heartburn exacerbation
HerbLemon BalmPregnancy SafetyLikely safeKey Concerns
Limited research, moderate amounts only
Based on American College of Obstetricians and Gynecologists guidelines

Teratogenic Potential

  • Valepotriate compounds: Linked to developmental abnormalities in animal studies
  • Placental transfer: Active compounds detected in fetal tissue
  • First trimester risk: Critical organ formation period vulnerability

Uterine Effects

  • Muscle stimulation: May trigger premature contractions
  • Hormonal influence: Potential progesterone pathway disruption
  • Blood flow impact: Altered uterine artery circulation

Delivery Complications

  • Labor interference: Possible sedation of newborn
  • Bleeding risk: Theoretical anticoagulant effects
  • Anesthesia interaction: Requires discontinuation 4 weeks pre-delivery

Crossing the placental barrier is a serious risk. The active substances of valerian, such as valerenic acid, cross into the fetal circulation, where they may impact the neurological development of the fetus. Animal studies have shown that doses equivalent to approximately therapeutic doses in humans can produce abnormal neural tube formation.

Major organizations, such as ACOG and the NHS, specifically say that valerian is unsafe in pregnancy. Due to the lack of human studies, we must therefore rely on pharmacological profiles, which theoretically indicate possible risks. When I check pregnant clients, I stress that the unknown dangers outweigh the theoretical benefits.

When dealing with pregnancy-related insomnia and anxiety, consider approved alternatives, such as prenatal yoga, meditation, or magnesium glycinate. Cognitive behavioral therapy for insomnia offers drug-free options. Anything recommended by your OB/GYN should take priority over experimenting with anything herbal while pregnant.

If you have taken valerian before knowing that you are pregnant, stop taking this herb immediately and contact your obstetrician. Although the risk is theoretical at this time, you should stop as soon as possible to minimize exposure. Please keep a record of any unusual symptoms and include them in your report to your healthcare provider.

Read the full article: Valerian Root Effects: Benefits and Risks Explained

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